Anti-mitochondrial antibody
Autoantibodies against liver mitochondria, indicating primary biliary cholangitis / From Wikipedia, the free encyclopedia
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Anti-mitochondrial antibodies (AMA) are autoantibodies, consisting of immunoglobulins formed against mitochondria,[1] primarily the mitochondria in cells of the liver.
The presence of AMA in the blood or serum of a person may be indicative of the presence of, or the potential to develop, the autoimmune disease primary biliary cholangitis (PBC; previously known as primary biliary cirrhosis). PBC causes scarring of liver tissue, confined primarily to the bile duct drainage system. AMA is present in about 95% of cases.[2] PBC is seen primarily in middle-aged women, and in those afflicted with other autoimmune diseases.