Bromocriptine
Dopamine agonist medication / From Wikipedia, the free encyclopedia
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Bromocriptine, originally marketed as Parlodel and subsequently under many brand names,[1] is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease, hyperprolactinaemia, neuroleptic malignant syndrome, and, as an adjunct, type 2 diabetes.
Quick Facts Clinical data, Trade names ...
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Trade names | Originally Parlodel, subsequently many[1] |
Other names | 2-Bromoergocriptine; CB-154 |
AHFS/Drugs.com | Monograph, International Drug Names |
MedlinePlus | a682079 |
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Routes of administration | By mouth, vaginal, intravenous |
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Bioavailability | 28% of oral dose absorbed |
Metabolism | Extensively liver-mediated |
Elimination half-life | 12–14 hours |
Excretion | 85% bile (feces), 2.5–5.5% urine |
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ECHA InfoCard | 100.042.829 |
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Formula | C32H40BrN5O5 |
Molar mass | 654.606 g·mol−1 |
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It was patented in 1968 and approved for medical use in 1975.[2]