Ets varijanta transkripcijskog faktora 2 je protein koji je kod ljudi kodiran genom ETV2.[5] To je faktor transkripcije i također ima ulogu u razvoju vaskularnih endotelnih ćelija.[6]
Kratke činjenice Identifikatori, Aliasi ...
Ets varijanta trankripcijskog faktora 2 |
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Identifikatori |
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Aliasi | ETV2 |
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Vanjski ID-jevi | OMIM: 609358 MGI: 99253 HomoloGene: 7308 GeneCards: ETV2 |
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Ontologija gena |
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Molekularna funkcija | • vezivanje sa DNK • sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
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Ćelijska komponenta | • jedro
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Biološki proces | • Notch signaling pathway • Ćelijska diferencijacija • positive regulation of endothelial cell differentiation • GO:0009373 regulation of transcription, DNA-templated • blood vessel morphogenesis • Placentacija • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • mesoderm formation • in utero embryonic development • Wnt-signalni put • transcription by RNA polymerase II • positive regulation of mesoderm development • GO:1901313 positive regulation of gene expression • BMP signaling pathway involved in mesodermal cell fate specification • erythrocyte differentiation • blastocyst development • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • Hematopoeza
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Izvori:Amigo / QuickGO |
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Ortolozi |
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Vrste | Čovjek | Miš |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNK) | | |
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RefSeq (bjelančevina) | | |
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Lokacija (UCSC) | Chr 19: 35.64 – 35.64 Mb | Chr 7: 30.33 – 30.34 Mb |
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PubMed pretraga | [3] | [4] |
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Wikipodaci |
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Zatvori