Antiglucocorticoid
Class of pharmaceutical drugs / From Wikipedia, the free encyclopedia
An antiglucocorticoid is a drug which reduces glucocorticoid activity in the body. They include direct glucocorticoid receptor antagonists such as mifepristone and synthesis inhibitors such as metyrapone, ketoconazole, and aminoglutethimide. They are used to treat Cushing's syndrome.
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Quick Facts Class identifiers, Synonyms ...
Antiglucocorticoid | |
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Drug class | |
Class identifiers | |
Synonyms | Glucocorticoid antagonist; Cortisol antagonist; Anticorticosteroid |
Use | Cushing's syndrome, others |
Biological target | Glucocorticoid receptor |
Chemical class | Steroids |
Legal status | |
In Wikidata |
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Antiglucocorticoids could be effective antidepressants for a subset of specific mood disorders, but their use is limited by side effects.[1]