Binding selectivity
In biochemistry, the preference of ligands to bind with one receptor over another / From Wikipedia, the free encyclopedia
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This article is about selectivity in chemical systems at equilibrium. For kinetic selectivity, see Reactivity–selectivity principle.
In chemistry, binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex. Binding selectivity describes how a ligand may bind more preferentially to one receptor than another. A selectivity coefficient is the equilibrium constant for the reaction of displacement by one ligand of another ligand in a complex with the substrate. Binding selectivity is of major importance in biochemistry[1] and in chemical separation processes.