Factor XIII
Class of enzymes / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Factor XIII?
Summarize this article for a 10 year old
SHOW ALL QUESTIONS
Factor XIII, or fibrin stabilizing factor, is a plasma protein and zymogen. It is activated by thrombin to factor XIIIa which crosslinks fibrin in coagulation. Deficiency of XIII worsens clot stability and increases bleeding tendency.[1]
Quick Facts coagulation factor XIII,A1 polypeptide, Identifiers ...
coagulation factor XIII, A1 polypeptide | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | F13A1 | ||||||
Alt. symbols | F13A | ||||||
NCBI gene | 2162 | ||||||
HGNC | 3531 | ||||||
OMIM | 134570 | ||||||
RefSeq | NM_000129 | ||||||
UniProt | P00488 | ||||||
Other data | |||||||
EC number | 2.3.2.13 | ||||||
Locus | Chr. 6 p24.2-p23 | ||||||
|
Close
Quick Facts coagulation factor XIII,B polypeptide, Identifiers ...
coagulation factor XIII, B polypeptide | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | F13B | ||||||
NCBI gene | 2165 | ||||||
HGNC | 3534 | ||||||
OMIM | 134580 | ||||||
RefSeq | NM_001994 | ||||||
UniProt | P05160 | ||||||
Other data | |||||||
Locus | Chr. 1 q31-q32.1 | ||||||
|
Close
Human XIII is a heterotetramer. It consists of 2 enzymatic A peptides and 2 non-enzymatic B peptides. XIIIa is a dimer of activated A peptides.[1]