KAT5
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Histone acetyltransferase KAT5 is an enzyme that in humans is encoded by the KAT5 gene.[5][6] It is also commonly identified as TIP60.
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.[6]