Mucin-5AC (MUC-5AC) is a protein that in humans is encoded by the MUC5AC gene.[5][6][7]
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MUC-5AC is a large gel-forming glycoprotein. In the respiratory tract it protects against infection by binding to inhaled pathogens that are subsequently removed by mucociliary clearance. Overproduction of MUC-5AC can contribute to diseases such as asthma and chronic obstructive pulmonary disease,[8] and has also been associated with greater protection against influenza infection.[9]