Parathion
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Parathion, also called parathion-ethyl or diethyl parathion and locally[clarification needed] known as "Folidol", is an organophosphate insecticide and acaricide. It was originally developed by IG Farben in the 1940s. It is highly toxic to non-target organisms, including humans, so its use has been banned or restricted in most countries. The basic structure is shared by parathion methyl.[5]
Quick Facts Names, Identifiers ...
Names | |
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Preferred IUPAC name
O,O-Diethyl O-(4-nitrophenyl) phosphorothioate | |
Other names
E605 | |
Identifiers | |
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3D model (JSmol) |
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2059093 | |
ChEBI | |
ChEMBL | |
ChemSpider |
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ECHA InfoCard | 100.000.247 |
EC Number |
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KEGG |
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PubChem CID |
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RTECS number |
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UNII | |
UN number | 3018 2783 |
CompTox Dashboard (EPA) |
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Properties | |
C10H14NO5PS | |
Molar mass | 291.26 g·mol−1 |
Appearance | White crystals (pure form) |
Melting point | 6 °C (43 °F; 279 K) |
24 mg/L | |
Solubility in other solvents | high solubility |
Hazards | |
GHS labelling: | |
Danger | |
H300, H311, H330, H372, H410 | |
P260, P264, P270, P271, P273, P280, P284, P301+P310, P302+P352, P304+P340, P310, P312, P314, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, P501 | |
NFPA 704 (fire diamond) | |
Flash point | 120 °C (248 °F; 393 K) |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
5 mg/kg (mouse, oral) 10 mg/kg (rabbit, oral) 3 mg/kg (dog, oral) 0.93 mg/kg (cat, oral) 5 mg/kg (horse, oral) 8 mg/kg (guinea pig, oral) 2 mg/kg (rat, oral)[1] |
LC50 (median concentration) |
84 mg/m3 (rat, 4 hr)[1] |
LCLo (lowest published) |
50 mg/m3 (rabbit, 2 hr) 14 mg/m3 (guinea pig, 2 hr) 15 mg/m3 (mouse)[1] |
NIOSH (US health exposure limits): | |
PEL (Permissible) |
none (methyl parathion),[2] TWA 0.1 mg/m3 [skin] (ethyl parathion)[3] |
REL (Recommended) |
TWA 0.2 mg/m3 [skin] (methyl parathion)[2] TWA 0.05 mg/m3 [skin] (ethyl parathion)[3] |
IDLH (Immediate danger) |
N.D. (methyl parathion)[2] 10 mg/m3 (ethyl parathion)[3] |
Safety data sheet (SDS) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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