Procaine benzylpenicillin
Antibiotic medication / From Wikipedia, the free encyclopedia
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Procaine benzylpenicillin also known as penicillin G procaine, is an antibiotic useful for the treatment of a number of bacterial infections.[2] Specifically it is used for syphilis, anthrax, mouth infections, pneumonia, diphtheria, cellulitis, and animal bites.[2] It is given by injection into a muscle.[2]
Combination of | |
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Benzylpenicillin | antibiotic |
Procaine | anaesthetic |
Clinical data | |
Trade names | Bicillin C-R,[1] other |
Other names | penicillin G procaine, procaine penicillin G, procaine penicillin |
AHFS/Drugs.com | FDA Professional Drug Information |
Routes of administration | IM |
ATC code | |
Legal status | |
Legal status |
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Identifiers | |
CAS Number |
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UNII | |
ChEMBL | |
E number | E707 (antibiotics) |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.000.187 |
NY (what is this?) (verify) |
Side effects include pain at the site of injection, blood clotting problems, seizures, and allergic reactions including anaphylaxis.[2] When used to treat syphilis a reaction known as Jarisch-Herxheimer may occur.[2] It is not recommended in those with a history of penicillin allergy or procaine allergy.[1][2] Use during pregnancy and breastfeeding is relatively safe.[1][2] Procaine benzylpenicillin is in the penicillin and beta lactam family of medications.[2] It works via benzylpenicillin and results in bacterial death.[2][3] Procaine makes the combination long acting.[4]
Procaine benzylpenicillin was introduced for medical use in 1948.[3] It is on the World Health Organization's List of Essential Medicines.[5]