Purine nucleoside phosphorylase
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Not to be confused with polynucleotide phosphorylase.
Purine nucleoside phosphorylase, PNP, PNPase or inosine phosphorylase (EC 2.4.2.1) is an enzyme that in humans is encoded by the NP gene.[2] It catalyzes the chemical reaction
- purine nucleoside + phosphate purine + alpha-D-ribose 1-phosphate
This article includes a list of general references, but it lacks sufficient corresponding inline citations. (September 2017) |
Quick Facts Identifiers, EC no. ...
purine-nucleoside phosphorylase | |||||||||
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Identifiers | |||||||||
EC no. | 2.4.2.1 | ||||||||
CAS no. | 9030-21-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Quick Facts Identifiers, Aliases ...
Purine nucleoside phosphorylase | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | Purine_phosphorylaseIPR011268 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | GeneCards: ; OMA:- orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Thus, the two substrates of this enzyme are a purine nucleoside and phosphate, whereas its products are a purine and alpha-D-ribose 1-phosphate.